Regenerative
GHK-Cu
Overview
GHK-Cu is the copper(II) complex of the human tripeptide GHK (glycyl-L-histidyl-L-lysine), a molecule naturally present in plasma that declines with age. It is one of the most extensively studied peptides in tissue-remodeling and skin-regeneration research.
Mechanism
GHK-Cu activates multiple remodeling processes: chemoattraction of repair cells, anti-inflammatory action, and increased synthesis of collagen, elastin, and glycosaminoglycans. Animal studies report accelerated wound healing, increased blood-vessel formation, and elevated antioxidant enzyme levels.
Research Areas
- Collagen, elastin, and glycosaminoglycan synthesis
- Wound-healing and tissue-remodeling models
- Antioxidant and anti-inflammatory signaling
Handling & Storage
Lyophilized; store refrigerated and protected from light. Reconstitute with bacteriostatic water for research use.
References
- 1.Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences (PubMed 29986520), 2018.
- 2.Pickart L, et al. The human tripeptide GHK and tissue remodeling. Journal of Biomaterials Science (PubMed 18644225), 2008.